Regulation of Sertoli Cell and Germ Cell Differentation

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Tight junctions found between Sertoli cells are the major component of this barrier in the adult testis. Sertoli cell tight junctions are required for fertility and we know that their disruption leads to germ cell atresia and cessation of spermatogenesis. We have conclusively shown that FSH and androgen controls the blood-testis barrier, which involves the tight junctions between Sertoli cells. As the blood-testis barrier is essential for the production of viable sperm, we have focussed our efforts on determining if regulation of the tight junctions is similar in humans. Skip to content Search for: Search.

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Regulation of Sertoli Cell Junctions | Hudson Institute of Medical Research

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Testosterone Retention Mechanism in Sertoli cells: A Biochemical Perspective

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Regulation of Sertoli Cell and Germ Cell Differentiation

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WT-1 is required for early kidney development.

Regulation of Sertoli cell and germ cell differentation.

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